COMPUTATIONAL MODELING TO IDENTIFY DRUGS TARGETING METASTATIC CASTRATION-RESISTANT PROSTATE CANCER CHARACTERIZED BY HEIGHTENED GLYCOLYSIS

Computational Modeling to Identify Drugs Targeting Metastatic Castration-Resistant Prostate Cancer Characterized by Heightened Glycolysis

Metastatic castration-resistant prostate cancer (mCRPC) remains a deadly disease due to a lack of efficacious treatments.The reprogramming of cancer metabolism toward elevated glycolysis is a hallmark of mCRPC.Our goal is to identify therapeutics specifically associated with high glycolysis.Here, we established a computational framework to identify

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From Smileys to Smileycoins: Using a copyright in Education

This paper describes a copyright to reward students for their studies.The currency bears the apt name Smileycoin or SMLY and is used within the tutor-web online learning platform.In order to make the SMLY attractive to students several approaches have been used, including Carpet support from companies whose services can be purchased for SMLY.The pa

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