Computational Modeling to Identify Drugs Targeting Metastatic Castration-Resistant Prostate Cancer Characterized by Heightened Glycolysis
Metastatic castration-resistant prostate cancer (mCRPC) remains a deadly disease due to a lack of efficacious treatments.The reprogramming of cancer metabolism toward elevated glycolysis is a hallmark of mCRPC.Our goal is to identify therapeutics specifically associated with high glycolysis.Here, we established a computational framework to identify